2006-03-01
Topical ibopamine in the treatment of chronic ocular hypotony attributable to vitreoretinal surgery, uveitis, or penetrating trauma
Publication
Publication
American Journal of Ophthalmology , Volume 141 - Issue 3 p. 571- 573
PURPOSE: To study whether topical ibopamine effectively increases the intraocular pressure in patients with ocular hypotony after vitreoretinal surgery, uveitis, or penetrating trauma. DESIGN: A prospective randomized, double-blind, placebo controlled, crossover study. METHODS: In ten patients with ocular hypotony, an ibopamine 2% solution or placebo eyedrop was administered at 8 am and frequent applanation tonometry was performed during 10 hours on 2 days, 2 weeks apart. RESULTS: The mean IOP integral after administration of ibopamine was 2.4 mm Hg higher (95% CI for median difference in AUC over 480 minutes [P = .010]) compared with placebo. CONCLUSIONS: The results of the study show that an ibopamine 2% eyedrop twice a day may increase the IOP for a period of over 8 hours in patients with hypotony.
Additional Metadata | |
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doi.org/10.1016/j.ajo.2005.09.034, hdl.handle.net/1765/60062 | |
American Journal of Ophthalmology | |
Organisation | Department of Ophthalmology |
Ugahary, L., Ganteris, E., Veckeneer, M., Cohen, A., Jansen, J., Mulder, P., & van Meurs, J. (2006). Topical ibopamine in the treatment of chronic ocular hypotony attributable to vitreoretinal surgery, uveitis, or penetrating trauma. American Journal of Ophthalmology, 141(3), 571–573. doi:10.1016/j.ajo.2005.09.034 |