2014-02-01
Application of single-vial ready-for-use formulation of 111In- or 177Lu-labelled somatostatin analogs
Publication
Publication
Applied Radiation and Isotopes , Volume 85 p. 28- 33
For the sake of safety it would be desirable to store and transport the ready-for-use liquid formulation (diagnostics and therapeutics) of radiolabelled peptides. The use of ethanol, in combination with a mixture of gentisic- and ascorbic acid, has superior effects on stabilizing radiolabelled somatostatin analogs. As a consequence, 111In- and 177Lu-labelled somatostatin analogs can be stored and transported in a single-vial ready-for-use liquid formulation up to 7 days after radiolabelling.
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| , , , , , | |
| doi.org/10.1016/j.apradiso.2013.10.023, hdl.handle.net/1765/61129 | |
| Applied Radiation and Isotopes | |
| Organisation | Department of Nuclear Medicine |
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de Blois, E., Chan, H. S., de Zanger, R., Konijnenberg, M., & Breeman, W. (2014). Application of single-vial ready-for-use formulation of 111In- or 177Lu-labelled somatostatin analogs. Applied Radiation and Isotopes, 85, 28–33. doi:10.1016/j.apradiso.2013.10.023 |
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