1995
Effect of an ACTH(4-9) analogue on cisplatin neuropathy of longstanding duration: A phase II study
Publication
Publication
Clinical Neurology and Neurosurgery , Volume 97 - Issue 2 p. 139- 141
The efficacy of Org 2766, an ACTH(4–9) analogue, on the recovery of cisplatin neuropathy of longstanding duration was investigated in a phase II study. Twenty-two patients were treated with Org 2766 during a period of 4 months and vibration perception threshold (VPT) and sum scores for neuropathic symptoms and signs were compared with pre-treatment values. No change in VPT could be detected. Although there was a small improvement of clinical measures for neuropathy, no clear evidence for repair could be obtained. These results indicate no beneficial effect of Org 2766 on recovery of a longstanding cisplatin neuropathy.
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| , , , | |
| doi.org/10.1016/0303-8467(95)00023-D, hdl.handle.net/1765/70910 | |
| Clinical Neurology and Neurosurgery | |
| Organisation | Department of Neurology |
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Hilkens, P. H. E., van der Burg, M., Moll, W., van den Bent, M., van Putten, W., & Vecht, C. (1995). Effect of an ACTH(4-9) analogue on cisplatin neuropathy of longstanding duration: A phase II study. Clinical Neurology and Neurosurgery, 97(2), 139–141. doi:10.1016/0303-8467(95)00023-D |
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