2012-05-01
Course of pandemic influenza A(H1N1) 2009 virus infection in Dutch patients
Publication
Publication
Influenza and Other Respiratory Viruses , Volume 6 - Issue 3
The clinical dynamics of influenza A(H1N1) 2009 infections in 61 laboratory-confirmed Dutch cases were examined. An episode lasted a median of 7·5days of which 2days included fever. Respiratory symptoms resolved slowly, while systemic symptoms peaked early in the episode and disappeared quickly. Severity of each symptom was rated highest in the first few days. Furthermore, diarrhoea was negatively associated with viral load, but not with faecal excretion of influenza virus. Cases with comorbidities appeared to have higher viral loads than the cases without, suggesting a less effective immune response. These results complement information obtained through traditional surveillance.
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| doi.org/10.1111/j.1750-2659.2012.00347.x, hdl.handle.net/1765/74019 | |
| Influenza and Other Respiratory Viruses | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Friesema, I. H. M., Meijer, A., van Gageldonk-Lafeber, R., van der Lubben, M., van Beek, J., Donker, G., … van der Sande, M. (2012). Course of pandemic influenza A(H1N1) 2009 virus infection in Dutch patients. Influenza and Other Respiratory Viruses, 6(3). doi:10.1111/j.1750-2659.2012.00347.x |
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