1990-03-01
Morphometrically estimated variation in nuclear size - A useful tool in grading prostatic cancer
Publication
Publication
Urological Research: a journal of clinical and laboratory investigation in urolithiasis and related areas , Volume 18 - Issue 2 p. 93- 99
At present there are several grading systems for prostatic carcinoma. Most are difficult to reproduce. An objective method of grading seems to be necessary and could make comparisons between various groups of patients easier and grading more reliable. In the present study morphometrically estimated nuclear size and variation in nuclear size are matched with the survival rates of 207 patients who underwent total perineal prostatetomy for cancer. On the basis of morphometrically estimated variation in nuclear size the patients could be divided into two groups with significantly differing survival rates. In this way it was possible to split the group of patients with grade 2 carcinoma (Mostofi's grading system) into two groups of patients with significantly different survival rates. The survival rates in these two groups did not differ significantly from those in the patients with Grade 1 and Grade 3 tumors respectively. The results are discussed in the light of the recent literature on the subject. Morphometry seems to be a valuable tool in grading prostatic cancer.
| Additional Metadata | |
|---|---|
| , , | |
| doi.org/10.1007/BF00302467, hdl.handle.net/1765/74397 | |
| Urological Research: a journal of clinical and laboratory investigation in urolithiasis and related areas | |
| Organisation | Department of Urology |
|
Blom, J., ten Kate, F., Schröder, F., & van der Heul, R. (1990). Morphometrically estimated variation in nuclear size - A useful tool in grading prostatic cancer. Urological Research: a journal of clinical and laboratory investigation in urolithiasis and related areas, 18(2), 93–99. doi:10.1007/BF00302467 |
|
