2013
T-cell suppression mediated by regulatory T cells infiltrating hepatic tumors can be overcome by GITRL treatment
Publication
Publication
OncoImmunology , Volume 2 - Issue 1
Recently, we reported the accumulation of CD4+FOXP3+ regulatory T cells (Tregs) within the tumor mass of patients bearing liver cancer. Tumor-infiltrating Tregs (TiTreg) are active and potent suppressors of antitumor immunity. Importantly, treatment with GITR L reduced the immunosuppression mediated by TiTreg.
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| , , , , , , , | |
| doi.org/10.4161/onci.22450, hdl.handle.net/1765/74860 | |
| OncoImmunology | |
| Organisation | Department of Gastroenterology & Hepatology |
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Pedroza-Gonzalez, A., Kwekkeboom, J., & Sprengers, D. (2013). T-cell suppression mediated by regulatory T cells infiltrating hepatic tumors can be overcome by GITRL treatment. OncoImmunology, 2(1). doi:10.4161/onci.22450 |
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