Hypertrophic cardiomyopathy (HCM) is an intriguing disease due to its heterogeneity in genetic, morphologic, and clinical spectrum. The insights in the prognosis and natural history of HCM have evolved tremendously over the past 40 years. The fi rst studies, which contained data derived from hospital-based populations, depicted a poor prognosis for HCM patients, in particular due to the high incidence of sudden cardiac death (SCD). More recent studies derived from community-based (or non-referral) centers suggest a more benign clinical course with an annual mortality of <1%. Another important fi nding is that most HCM patients remain a lifetime without symptoms.

Additional Metadata
Promotor Simoons, M.L. (Maarten)
Publisher Erasmus University Rotterdam
Sponsor Netherlands Heart Foundation , Simoons, Prof. Dr. M.L.
ISBN 978-908559-149-8
Persistent URL hdl.handle.net/1765/7553
Citation
van der Lee, C.. (2006, March 8). Hypertrophic Cardiomyopathy Update on Prognosis and Therapy. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/7553