Aplastic anaemia: a review
January 2003
Article
| Related Files |
|---|
View PDF Version
(12916541.pdf, 0.1MB) |
Aplastic anaemia is featured by bone marrow hypocellularity and peripheral pancytopenia and is a potentially fatal disease. In recent years, insight in it pathogenesis has increased. It appears that activated autoreactive T lymphocytes induce apoptosis of haematopoietic stem cells resulting in a hypocellular bone marrow. Nowadays, it can be treated by stem cell transplantation or immunosuppressive therapy. This review focuses on the pathophysiology and treatment of aplastic anaemia.
Keywords
Automatically Extracted Terms
- aplastic anaemia
- aplastic
- anaemia
- patient
- aplastic anemia
- marrow
- treatment
- anemia
- bone marrow transplantation
- transplantation
- blood
- allo-sct
- antithymocyte globulin
- bone marrow
- globulin
- therapy
- survival
- response
- haematol
- result
