Improved detection of methicillin-resistant Staphylococcus aureus using phenyl mannitol broth containing aztreonam and ceftizoxime.
2001-07-14
Article
volume 39, issue 7 pp 2660-2662.
| Related Files |
|---|
|
Redirect to publisher's version
(publisher's version.url.txt, 31 bytes) |
Repository contains one additional file which is not publicly available
We tested a phenyl mannitol broth containing ceftizoxime and aztreonam (PHMB(+)) for detection of methicillin-resistant Staphylococcus aureus (MRSA) with reference MRSA strains and, subsequently, with clinical samples (n = 1,098). All reference MRSA strains induced color change in PHMB(+) after 24 to 72 h of incubation. In a clinical setting, 40 MRSA strains were detected with PHMB(+), compared with only 23 detected with a routine method. Thus, this selective broth significantly (P < 0.001) improved the rate of MRSA detection.
Keywords
- Humans
- Staphylococcal Infections/microbiology
- *Methicillin Resistance
- Bacteriological Techniques
- Culture Media/chemistry
- Aztreonam/pharmacology
- Ceftizoxime/pharmacology
- Cephalosporins/pharmacology
- Mannitol/*metabolism
- Monobactams/pharmacology
- Phenolsulfonphthalein/*metabolism
- Staphylococcus aureus/classification/*drug effects/growth & development/*isolation & purification