Staphylococcus aureus carriage patterns and the risk of infections associated with continuous peritoneal dialysis.
June 2006
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The epidemiology and risks of Staphylococcus aureus carriage in continuous peritoneal dialysis (CPD) patients was studied in a single tertiary-care institution. On outpatient visits samples for culture were routinely taken prospectively from the CPD catheter exit site and the vestibulum nasi. Seventy-five patients with at least one culture positive for S. aureus in this period were included: 43 had genotypically identical S. aureus strains in over 80% of the cultures and were classified as persistent carriers; 32 were intermittent carriers. Persistent carriage was associated with a threefold higher risk for CPD-related infections and sixfold higher rates of vancomycin consumption compared to those for the intermittent carriers. No methicillin or vancomycin resistance was detected.
- Male
- Adult
- Aged
- Female
- Humans
- Middle aged
- Risk Factors
- Adolescent
- Carrier State/*epidemiology/*microbiology
- Nose/microbiology
- Peritoneal Dialysis, Continuous Ambulatory/*adverse effects
- Staphylococcal Infections/*epidemiology/microbiology
- Staphylococcus aureus/*isolation & purification