http://hdl.handle.net/1765/18168

Regulation of prostate-specific antigen expression

(Regulering van prostaat-specifiek antigeen expressie)


Doctoral Thesis
Published by
Related Files
asset icon
(970625_CLEUTJENS, Catharina Barbara Josephine Maria.pdf, 5.2MB)
asset icon
(stellingen cleutjens.pdf, 0.1MB)

Steroid hormones are widely distributed, cholesterol-derived, small hydrophobic molecules. They mediate a variety of biological functions, including tissue development, differentiation and homeostasis. Mammalian steroid hormones (androgens, glucocorticoids, mineralocorticoids, estrogens and progestins) exert their function by binding to the corresponding intracellular steroid hormone receptor. This binding triggers a complex set of molecular events, including protein-protein and protein-DNA interactions.


Supervisor (promotor):

Prof. Dr. Bosman, F.T.

The author wishes to thank:

Stichting Nederlandse Kankerbestrijding


Keywords


Automatically Extracted Terms
  • receptor
  • prostate
  • promoter
  • androgen
  • activity
  • expression
  • binding
  • lncap
  • region
  • hormone
  • psa promoter
  • factor
  • transcription
  • protein
  • sequence
  • cancer
  • lncap cells
  • enhancer
  • figure
  • element


Bookmark with: