Specific Diagnostic Tests for Atypical Respiratory Tract Pathogens
March 2010
Article
volume 24, issue 1 pp 229-248.
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This article reviews the microbiological diagnostic tests that are currently available for the detection of M pneumoniae, C pneumoniae, and Legionella spp; their clinical performance; and their future in the clinical microbiology laboratory. When implementing a strategy, a balance between performance criteria (sensitivity, specificity) and convenience criteria (clinical utility, turnaround time, and costs) will have to be defined. In the end, this should result in the optimization of clinical patient management.
Keywords
- human
- disease severity
- nonhuman
- intermethod comparison
- sensitivity and specificity
- diagnostic accuracy
- review
- real time polymerase chain reaction
- nucleotide sequence
- enzyme linked immunosorbent assay
- diagnostic value
- bacterium culture
- urinalysis
- gold standard
- multiplex ligation dependent probe amplification
- Mycoplasma pneumoniae
- Mycoplasma pneumonia
- bacterium detection
- analytic method
- Chlamydophila pneumoniae
- Diagnostic tests
- Legionella pneumophila
- antigen detection
- bacterial antigen
- chlamydial pneumonia
- community acquired pneumonia
- legionnaire disease
- nucleic acid amplification
- pertussis
- serodiagnosis
- strand displacement amplification
- tularemia
- turnaround time
