Should prostate tumor volume routinely be reported by the pathologist?: The prognostic value of tumor volume in prostate cancer [Moet het prostaattumorvolume standaard worden vermeld door de patholoog? De prognostische waarde van tumorvolume in prostaatkanker]
Tumor volume was measured in 344 totally embedded radical prostatectomy specimens of screen detected prostate cancer cases. In univariate analyses, tumor volume was predictive for biochemical and local progression, metastasis and mortality. In multivariable analyses, tumor volume did not add prognostic value to routinely assessed pathological parameters, like tumor stage, Gleason score, seminal vesicle invasion and surgical margin status. Therefore, there seems to be little reason to routinely measure tumor volume in RP specimens.