http://hdl.handle.net/1765/21468
isbn: 978-907343-621-3

Cytokines and T lymphocytes in transplantation : targets for immunotherapy

(Cytokinen en T lymfocyten in transplantatie: doelen voor immunotherapie)


Doctoral Thesis
Published by
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Organ transplantation has become an established therapy in patients suffering from diseases leading to organ failure. Table I shows the number of organ transplants performed in the Eurotransplant area from 1 g90 to 1993. The use of potent immunosuppressive drugs and effective protocols for prevention and treatment of infectious diseases have contributed to improved outcome of clinical organ transplantation. Nowadays, one-year patient and graft survival after kidney transplantation is 85 to 95 % (1). However, the potent immune response to transplanted tissues leading to acute graft rejection remains a major problem.


Supervisor (promotor):

Prof. Dr. Benner, R.

The author wishes to thank:

Dutch Kidney Foundation,


Keywords


Automatically Extracted Terms
  • anti-cd 3 mab
  • anti-cd
  • cytokine
  • rejection
  • effect
  • graft
  • release
  • antibody
  • treatment
  • allograft
  • 145-2
  • tnf-a
  • skin allograft rejection
  • transplantation
  • anti-cd 3
  • level
  • receptor
  • serum
  • binding
  • side effects


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