Experimental pandemic (H1N1) 2009 virus infection of cats
October 2010
Article
volume 16, issue 11 pp 1745-1747.
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To demonstrate that pandemic (H1N1) 2009 virus may cause respiratory disease in cats, we intratracheally infected cats. Diffuse alveolar damage developed. Seroconversion of sentinel cats indicated cat-to-cat virus transmission. Unlike in cats infected with highly pathogenic avian influenza virus (H5N1), extrarespiratory lesions did not develop in cats infected with pandemic (H1N1) 2009 virus.
Keywords
- article
- female
- human
- controlled study
- Netherlands
- animal tissue
- nonhuman
- child
- human tissue
- preschool child
- blood sampling
- polymerase chain reaction
- histopathology
- case report
- pathogenesis
- influenza A (H1N1)
- pandemic influenza
- antibody titer
- antigen expression
- virus isolation
- neutrophil chemotaxis
- lung injury
- plasma cell
- macrophage
- lymphocyte
- experimental cat
- cytokeratin
- lung infiltrate
- lymphocytolysis
- reverse transcription
- sinus histiocytosis
- virus nucleoprotein
