Modulation of determinants of myocardial function and energetics by stunning and heart failure
(Effect van stunning en hartfalen op determinanten van hartfunctie en energetica)
1996-11-27
Doctoral Thesis
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Diminished contractile function may occur in regional myocardium or present itself as global hypokinesis. Abnormality in contractile function of regional myocardium is usually the result of ischemia with or without subsequent restoration of blood flow, while global hypokinesis is often seen in congestive heart failure. Experimental investigations, however, have implicated that, among other factors, an abnonnality in excitation contraction coupling of the myocardium could serve as a potential mechanism for both regional and global contractile abnormality.
Supervisors
(promotores):
The
author
wishes to thank:
Netherlands Heart Foundation
Keywords
Automatically Extracted Terms
- myocardium
- length
- heart
- force
- function
- calcium
- contractile
- effect
- change
- study
- sarcomere length
- efficiency
- segment
- sarcomere
- decrease
- relation
- infusion
- muscle
- ladca
- emd 60263
