Cytokine dependence of B cell memory formation : a study in mice with emphasis on IgG1, and IgE
(Cytokine afhankelijkheid van d geheugen B cel vorming: Een studie in de muis met speciale aandacht voor IgG, en IgE)
1994-11-23
Doctoral Thesis
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Mammals are born with virtually no self-generated immune protection. Immediately after birth they are more or less protected by antibodies that have crossed the placenta or are derived from the colostrum. This so called passive-immunization only holds for a limited period after birth. When the new-born is exposed to environmental antigens the immune-defense systems are gradually built up_ This natural form of active immunization can be mimicked by a deliberate introduction of antigens into the host in order to provoke protective immune responses prior to a natural encounter with those antigens [Clark, 1991]
Supervisor
(promotor):
The
author
wishes to thank:
NWO
Pfizer BV
Keywords
Automatically Extracted Terms
- il -4
- b cells
- response
- level
- memory
- t cells
- serum
- production
- control
- result
- il -4 treatment
- treatment
- isotype
- antigen
- ige responses
- antibody
- immunol
- cytokine
- spleen cells
- spleen
