Structure of the murine Thy-1 gene
January 1985
Article
volume 4 pp 2017-2024.
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We have cloned the murine Thy-1.1 (AKR) and Thy-1.2 (Balb/c) genes. The complete exon/intron structure and the nucleotide sequence of the Thy-1.2 gene was determined. The gene contains four exons and three intervening sequences. The complete transcriptional unit gives rise to a tissue and developmental stage-specific mRNA of 1850 bp. The 5' end of the gene has multiple initiation sites and a non-TATA box promoter. The 3' end shows a single polyadenylation site after a very long untranslated region.
Keywords
- Animals
- 0 (Plasmids)
- 9007-49-2 (dna)
- Comparative Study
- Human
- Plasmids
- Support, Non-U.S. Gov't
- Amino Acid Sequence
- Mice
- Transfection
- Base Sequence
- Hela Cells
- *Cloning, Molecular
- 0 (RNA, Messenger)
- RNA, Messenger/genetics
- Rats
- *Genes, Structural
- Transcription, Genetic
- Species Specificity
- Mice, Inbred Strains
- DNA Restriction Enzymes
- EC 3.1.21 (DNA Restriction Enzymes)
- 0 (Antigens, Surface)
- 0 (Antigens, Thy-1)
- Antigens, Surface/*genetics
- Antigens, Thy-1
- DNA/*analysis
