http://hdl.handle.net/1765/30308

pubmed: 18176077
scopus: 38849142497



Diagnostic accuracy of consensus diagnostic criteria for frontotemporal dementia in a memory clinic population


Article
volume 25, issue 2 pp 157-164.
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Background/Aims: The goal of the present study was to evaluate the diagnostic accuracy of the core diagnostic criteria for frontotemporal dementia (FTD) [Neary D, et al: Neurology 1998;51:1546-1554] within a memory clinic population. Methods: The 5 core diagnostic criteria for FTD were operationalised in an informant-based written questionnaire. For a diagnosis of FTD the total clinical picture was weighted with findings on additional investigations and possible exclusion criteria, with follow-up of at least 1 year. Results: The operationalised core criteria for FTD had a sensitivity of 79% (95% CI = 57-92) and a specificity of 90% (95% CI = 85-94). Conclusion: The core diagnostic criteria for FTD applied in a caregiver questionnaire have good diagnostic accuracy among subjects without advanced dementia attending a memory clinic. This stresses the importance of the informant-based history in the differential diagnosis of dementia. Copyright



Keywords


Automatically Extracted Terms
  • criteria
  • dementia
  • diagnosis
  • frontotemporal dementia
  • patient
  • questionnaire
  • behaviour
  • subject
  • frontotemporal
  • behavioural
  • sensitivity
  • change
  • caregiver
  • study
  • question
  • accuracy
  • memory
  • disturbance
  • clinic
  • specificity


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