EUR > Medicine & Health > Erasmus MC > View Doctoral Thesis
http://hdl.handle.net/1765/31099
isbn: 978-90-5335-501-5

Risk Factors in Cause and Course of Multiple Sclerosis

(Risicofactoren betreffend het ontstaan en beloop van multiple sclerose)


Doctoral Thesis
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Multiple sclerosis (MS) is a leading non-traumatic cause of disability in young adults. It is a chronic neurological disorder characterized primarily by central nervous system (CNS) inflammation, myelin loss, and axonal pathology, resulting in progressive neurological dysfunction. Initially, inflammation is transient and partial remyelination occurs. MS is presumed to be an autoimmune disorder arising from complex interactions of both environmental and genetic factors.


Supervisor (promotor):

Prof. Dr. Hintzen, R.Q.

The author wishes to thank:

Erasmus University Rotterdam
J.E. Juriaanse Stichting
Boehringer Ingelheim B.V.
Biogen idec International B.V.
Novaritis Pharma B.V.
Sanofi-avenis Netherlands B.V.
Stichting MS Research


Keywords


Automatically Extracted Terms
  • study
  • sclerosis
  • smoking
  • patient
  • factor
  • disease
  • association
  • lesion
  • chapter
  • cigarette smoking
  • cigarette
  • criteria
  • risk factors
  • neurol
  • allele
  • ms patients
  • virus
  • control
  • effect
  • susceptibility


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