Functional analysis of the transcription factors Sp3 and Sp4

(Functionele analyse van de transcriptie factoren Sp3 en Sp4)


Doctoral Thesis
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Biological processes are largely controlled by the synthesis and the modulation of proteins. For the synthesis of proteins. two steps are of critical importance. Firstly, the genetic information for the protein has to be transcribed from the DNA of the gene encoding the protein to the mRNA intermediate and secondly the mRNA has to be translated into the amino acid sequence that forms the protein.


Supervisor (promotor):

Prof. Dr. Grosveld, F.G.


Keywords


Automatically Extracted Terms
  • transcription
  • factor
  • protein
  • expression
  • development
  • knockout
  • domain
  • promoter
  • binding
  • transcription factors
  • activation
  • mouse
  • function
  • heart
  • regulation
  • suske
  • embryo
  • family
  • finger
  • phenotype