Aspects of plasma triglyceride metabolism in children

This thesis aimed at investigating some aspects of plasma triglyceride metabolism in children. In the introduction general aspects of plasma triglyceride metabolism are presented. Chapter 1 reviews recent litterature data on the intravenous fat tolerance test and on plasma postheparin lipoprotein lipase activity (PHLPL) in different situations associated with abnormal plasma triglyceride concentration. Chapter 2 defines the subjects of investigation. They are: 1 Plasma triglyceride metabolism in children with glycogen storage disease. 2 Plasma triglyceride metabolism in obese children. 3 The use of lntralipid fat emulsion during total parenteral nutrition. The methods used in these investigations are described. They are the intravenous fat tolerance test (IVFTT) and the measurement of plasma PHLPL activity. A method for calculating relative triglyceride production rate is also presented.