http://hdl.handle.net/1765/3318
http://dx.doi.org/10.1016/0166-3542(87)90030-1
scopus: cited times
web of science: cited 14 times
http://dx.doi.org/10.1016/0166-3542(87)90030-1
scopus: cited times
web of science: cited 14 times
Selective inhibitory effects of (S)-9-(3-hydroxy-2-phosphonyl-methoxypropyl)adenine and 1-(2'-deoxy-2'-fluoro-ß-D-arabinofuranosyl)-5-iodouracil on seal herpesvirus (Phocid herpesvirus 1) infection in vitro.
January 1987
Article
volume 7, issue 4 pp 221-226.
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From a selection of 25 antiviral compounds with specific anti-herpes activity or broad-spectrum antiviral properties, two compounds, namely (S)-9-(3-hydroxy-2-phosphonyl-methoxypropyl)adenine and 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil, appeared particularly effective in inhibiting the cytopathogenicity of seal herpesvirus (phocid herpesvirus 1).
Keywords
- Animals
- Support, Non-U.S. Gov't
- Cells, Cultured
- Antiviral Agents/*pharmacology
- *Organophosphorus Compounds
- 0 (Antiviral Agents)
- 0 (Organophosphorus Compounds)
- 3083-77-0 (Arabinofuranosyluracil)
- 58-96-8 (Uridine)
- 69123-98-4 (fialuridine)
- 73-24-5 (Adenine)
- 92999-29-6 (9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine)
- Adenine/*analogs & derivatives/pharmacology
- Arabinofuranosyluracil/*analogs & derivatives/pharmacology
- Herpesviridae/*drug effects
- Seals/microbiology
- Uridine/*analogs & derivatives
Automatically Extracted Terms
- e h v
- compound
- n t i
- activity
- courtesy
- agent
- test compounds
- clercq
- virus
- herpesviru
- agents chemother
- tissue culture medium
- t h e
- herpes simplex virus
- u.s.a
- synthesis
- nucleoside
- effect
- culture
- research