Selective inhibitory effects of (S)-9-(3-hydroxy-2-phosphonyl-methoxypropyl)adenine and 1-(2'-deoxy-2'-fluoro-ß-D-arabinofuranosyl)-5-iodouracil on seal herpesvirus (Phocid herpesvirus 1) infection in vitro.


Article
volume 7, issue 4 pp 221-226.
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From a selection of 25 antiviral compounds with specific anti-herpes activity or broad-spectrum antiviral properties, two compounds, namely (S)-9-(3-hydroxy-2-phosphonyl-methoxypropyl)adenine and 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil, appeared particularly effective in inhibiting the cytopathogenicity of seal herpesvirus (phocid herpesvirus 1).



Keywords


Automatically Extracted Terms
  • e h v
  • compound
  • n t i
  • activity
  • courtesy
  • agent
  • test compounds
  • clercq
  • virus
  • herpesviru
  • agents chemother
  • tissue culture medium
  • t h e
  • herpes simplex virus
  • u.s.a
  • synthesis
  • nucleoside
  • effect
  • culture
  • research