The haemodynamic and myocardial effects of dopexamine: a new B2-adrenoceptor and dopaminergic agonist
January 1986
Article
volume 21 pp 393-400.
(British Journal of Clinical Pharmacology)
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Dopexamine increases inotropic state and rate of relaxation independent of changes in heart rate. Dopexamine has a chronotropic effect and results in a decrease in systemic vascular resistance. Dopexamine has a spectrum of action that should be useful in patients with severe heart failure.
Keywords
- Male
- Human
- Adult
- Aged
- Female
- Middle Aged
- Support, U.S. Gov't, P.H.S.
- Blood Pressure/drug effects
- Heart Rate/drug effects
- Hemodynamic Processes/*drug effects
- Myocardial Contraction/drug effects
- Vascular Resistance/drug effects
- Heart/*drug effects
- 0 (Receptors, Dopamine)
- 51-61-6 (Dopamine)
- 86197-47-9 (dopexamine)
- 0 (Adrenergic beta-Agonists)
- Adrenergic beta-Agonists/pharmacology
- Dopamine/*analogs & derivatives/pharmacology
- Drug Evaluation
- Heart Failure, Congestive/drug therapy
- Receptors, Dopamine/drug effects
