Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease
January 1990
Article
volume 108 pp 350-354.
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Serum levels of interleukin-6 (IL-6) were determined in 97 patients with clinically diagnosed Alzheimer's disease and 79 age- and sex-matched control subject. Median serum levels of IL-6 did not differ significantly between Alzheimer patients (8.6 U/ml) and controls (8.2 U/ml). Median levels of serum IL-6 were similar for sporadic and familial patients. The concentration of IL-6 was not associated with the severity of the dementia or the duration of the disease since first symptoms. According to these observations there is no evidence for a significant elevation in serum IL-6 in Alzheimer's disease.
Keywords
- Human
- Support, Non-U.S. Gov't
- Aged
- Middle Aged
- Interleukin-6/blood
- dementia
- 0 (Interleukin-6)
- Alzheimer Disease/immunology
Automatically Extracted Terms
- patient
- disease
- serum
- alzheimer
- il -6
- level
- serum il -6
- control
- dementia
- interleukin
- protein
- serum levels
- interleukin -6
- acute-phase
- study
- amyloid
- response
- arthritis
- subject
- range
