Efficacy of mupirocin nasal ointment in eradicating Staphylococcus aureus nasal carriage in chronic haemodialysis patients
January 1991
Article
volume 17, issue 2 pp 133-137.
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Topical 2% mupirocin ointment eradicated chronic Staphylococcus aureus nasal carriage immediately post-therapy in 17 (77%) of 22 haemodialysis patients. Mean time to recurrence was 3.8 weeks. Similar pre-therapy and post-therapy phage types occurred in 12 (71%) of 17 patients. Staphylococcus aureus infections developed in none of 17 successfully treated patients, two of five treatment failures (P = 0.05), and 10 of 46 untreated patients studied concurrently (P = 0.03).
Keywords
- human
- mupirocin
- fatty acids/therapeutic use
- renal dialysis
- recurrence
- antibiotics/therapeutic use
- carrier state/microbiology
- oitments
- support, non-U.S. government
- pilot projects
- nasal ucosa/microbiology
- staphylococcus aureus/drug effects/growth & development
Automatically Extracted Terms
- patient
- mupirocin
- carriage
- staphylococcus
- aureus
- infection
- haemodialysi
- haemodialysis patients
- therapy
- study
- post-therapy
- staphylococcus aureus
- aweus infections
- month
- culture
- staphylococcus aweus
- staphylococcus aureus infections
- relapse
- post-therapy phage types
- phage types