Nasal carriage of Staphylococcus aureus treated with topical mupirocin (pseudomonic acid) in a children's hospital
January 1989
Article
volume 13, issue 2 pp 117-120.
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2% mupirocin ointment applied intra-nasally for 5 days was assessed for elimination of nasal carriage of Staphylococcus aureus in 31 staff members in a children's hospital. Three volunteers failed to complete the trial because of side effects, i.e. buccal reddening and swelling, and unpleasant taste. During treatment staphylococcal nasal carriage was not found in any case; of the 24 post-treatment nasal swabs taken 4 days after treatment 22 were still negative. Re-colonization with S. aureus of different phage types occurred in the remaining two cases.
Keywords
- female
- human
- male
- child
- administration, intranasal
- antibiotics/administration & dosage/pharmacology
- carrier state
- cross infection/prevention & control
- fatty acids/administration & dosage/pharmacology
- hospitalization
- mupirocin
- nose/microbiology
- staphylococcal infections/prevention & control
- staphylococcus aureus/drug effects
Automatically Extracted Terms
- pseudomonic acid
- mupirocin
- pseudomonic
- staphylococcus aureus
- carriage
- aureus
- treatment
- volunteer
- staphylococcus
- hospital
- study
- journal
- phage types
- ointment
- mellow
- activity
- 4 days
- elimination
- casewell
- antibiotic
