Bacterial cholangitis causing secondary sclerosing cholangitis: a case report
January 2002
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BACKGROUND: Although bacterial cholangitis is frequently mentioned as a cause of secondary sclerosing cholangitis, it appears to be extremely rare, with only one documented case ever reported. CASE PRESENTATION: A 48-year-old woman presented with an episode of acute biliary pancreatitis that was complicated by pancreatic abcess formation. After 3 months she had an episode of severe pyogenic (E. Coli) cholangitis that recurred over the subsequent 7 months on a further two occasions. Initially, cholangiography suggested the presence of extra-biliary intrahepatic abcesses while repeated investigations demonstrated development of multiple segmental biliary duct strictures. After maintenance antibiotic treatment was started, no episodes of cholangitis occurred over a 14-month period. CONCLUSIONS: Sclerosing cholangitis can rapidly develop after an episode of bacterial cholangitis. Extra-biliary involvement of the hepatic parenchyma with abcess formation may be a risk factor for developing this rare but particularly severe complication.
- Female
- Humans
- Middle aged
- Cholangiopancreatography, Endoscopic Retrograde
- Abdominal Abscess/*complications
- Cholangitis, Sclerosing/*etiology/microbiology/radiography
- Cholangitis/*complications/microbiology
- Escherichia coli Infections/*complications/*diagnosis
- Liver Diseases/*complications
- Pancreatic Diseases/*complications
- cholangiti
- biliary
- patient
- sclerosing cholangitis
- episode
- sclerosing
- biliary tree
- strictures
- page number
- month
- gastroenterology
- citation purposes
- abcesse
- presence
- suppurative cholangitis
- serum bilirubin level
- pyogenic cholangitis
- maintenance antibiotic treatment
- hepatic
- figure
