Congenital mesoblastic nephroma 50 years after its recognition: A narrative review
Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.
|Keywords||clinical characteristics, congenital mesoblastic nephroma, genetics, histology, infancy, outcome, renal tumor, review, treatment|
|Persistent URL||dx.doi.org/10.1002/pbc.26437, hdl.handle.net/1765/100063|
|Journal||Pediatric Blood & Cancer|
|Grant||This work was funded by the European Commission 7th Framework Programme; grant id fp7/261474 - EUROPEAN NETWORK for CANCER research in CHILDREN and ADOLESCENTS (ENCCA)|
Gooskens, S.L.M, Houwing, M.E, Vujanic, G.M, Dome, J.S, Diertens, T., Coulomb-L'Herminé, A, … van den Heuvel-Eibrink, M.M. (2017). Congenital mesoblastic nephroma 50 years after its recognition: A narrative review. Pediatric Blood & Cancer (Vol. 64). doi:10.1002/pbc.26437