Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.

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Keywords clinical characteristics, congenital mesoblastic nephroma, genetics, histology, infancy, outcome, renal tumor, review, treatment
Persistent URL dx.doi.org/10.1002/pbc.26437, hdl.handle.net/1765/100063
Journal Pediatric Blood & Cancer
Grant This work was funded by the European Commission 7th Framework Programme; grant id fp7/261474 - EUROPEAN NETWORK for CANCER research in CHILDREN and ADOLESCENTS (ENCCA)
Citation
Gooskens, S.L.M, Houwing, M.E, Vujanic, G.M, Dome, J.S, Diertens, T., Coulomb-L'Herminé, A, … van den Heuvel-Eibrink, M.M. (2017). Congenital mesoblastic nephroma 50 years after its recognition: A narrative review. Pediatric Blood & Cancer (Vol. 64). doi:10.1002/pbc.26437