NSAIDs for chronic low back pain
CLINICAL QUESTION Are nonsteroid alanti-inflammatory drugs (NSAIDs) associated with greater pain relief than placebo, other drugs, and nondrug treatments for patients with chronic lowback pain?
BOTTOM LINE Compared with placebo, NSAIDs are associated with a small but significant improvement in pain and disability in patients with chronic low back pain, although this difference became nonsignificant when studies with high risk for bias were excluded. The associated benefits were smaller than the minimal clinically important difference.
|Persistent URL||dx.doi.org/10.1001/jama.2017.4571, hdl.handle.net/1765/100617|
|Journal||J A M A: The Journal of the American Medical Association|
|Note||Not covered by the subscription|
Enthoven, W.T.M, Roelofs, P.D.D.M, & Koes, B.W. (2017). NSAIDs for chronic low back pain. J A M A: The Journal of the American Medical Association (Vol. 317, pp. 2327–2328). doi:10.1001/jama.2017.4571