Dusingize et al. used a prospective observational cohort study to demonstrate a decreased risk of basal cell carcinoma and an increased risk of squamous cell carcinoma among smokers. This association disappeared after stratifying for skin screening visits, demonstrating the important role of detection bias. In the absence of randomized clinical trials, well-designed and critically analyzed observational studies can provide similarly valuable evidence.

Additional Metadata
Persistent URL dx.doi.org/10.1016/j.jid.2017.05.002, hdl.handle.net/1765/100957
Journal The Journal of Investigative Dermatology
Wakkee, M. (2017). Smokers versus Smoking: Is There Detection Bias for Keratinocyte Carcinomas?. The Journal of Investigative Dermatology (Vol. 137, pp. 1614–1616). doi:10.1016/j.jid.2017.05.002