Nutritional and Cellular Preconditioning in Ischemia-reperfusion Injury

We investigated the impact of donor type on transcriptional changes that occur after organ retrieval and cold storage in kidneys and livers from living donors, DCD and DBD donors.
Further studies describe the use of nutritional preconditioning and infusion of mesenchymal stem cells as possible treatments to ameliorate IRI.
Finally, a mouse model with reduced expression of Fibulin-4 was used to study the local and systemic effects of renal IRI in short- and long-term.