Purpose: To describe a clinical case of biopsy-proven Merkel cell carcinoma of the eyelid following golimumab therapy for rheumatoid arthritis (RA). Methods: Interventional case report. Results: A 73-year-old woman with a history of chronic RA presented with a right upper eyelid mass. She had been treated with golimumab (tumor necrosis factor (TNF) inhibitors) injection therapy for the past 6 months. A biopsy showed findings suggestive of a Merkel cell carcinoma of the eyelid. Conclusions: Merkel cell carcinoma may be associated with anti-TNF treatment and should be included in the differential diagnosis of an eyelid tumor in patients treated with TNF inhibitors.

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doi.org/10.1080/01676830.2017.1353118, hdl.handle.net/1765/101695
Erasmus MC: University Medical Center Rotterdam

Hanafi, H., Verdijk, R., & Paridaens, D. (2017). Eyelid Merkel cell carcinoma in a patient treated with golimumab. Orbit, 1–5. doi:10.1080/01676830.2017.1353118