Purpose: To describe a clinical case of biopsy-proven Merkel cell carcinoma of the eyelid following golimumab therapy for rheumatoid arthritis (RA). Methods: Interventional case report. Results: A 73-year-old woman with a history of chronic RA presented with a right upper eyelid mass. She had been treated with golimumab (tumor necrosis factor (TNF) inhibitors) injection therapy for the past 6 months. A biopsy showed findings suggestive of a Merkel cell carcinoma of the eyelid. Conclusions: Merkel cell carcinoma may be associated with anti-TNF treatment and should be included in the differential diagnosis of an eyelid tumor in patients treated with TNF inhibitors.

Additional Metadata
Keywords Golimumad, Merkel cell carcinoma, rheumatoid arthritis, TNF inhibitors
Persistent URL dx.doi.org/10.1080/01676830.2017.1353118, hdl.handle.net/1765/101695
Journal Orbit
Citation
Hanafi, H, Verdijk, R.M, & Paridaens, A.D.A. (2017). Eyelid Merkel cell carcinoma in a patient treated with golimumab. Orbit, 1–5. doi:10.1080/01676830.2017.1353118