The cohesin complex has evolved as major player for structuring the chromatin fiber with roles in chromosome segregation, chromatin architecture, DNA damage repair and gene regulation. This article summarizes the latest discoveries and models for cohesin function and also reviews implications of the cohesin complex in developmental syndromes and cancer.

Additional Metadata
Persistent URL dx.doi.org/10.1007/s12268-017-0834-0, hdl.handle.net/1765/101902
Journal BioSpektrum
Citation
Wendt, K.S. (2017). Cohesin – ein Proteinring für Genomstabilität und Chromatinfaltung. BioSpektrum (Vol. 23, pp. 519–521). doi:10.1007/s12268-017-0834-0