Systemic corticosteroids are known to cause an iatrogenic Cushing's syndrome. Recent research indicates that topical corticosteroids, including widely used topical corticosteroids in dermatology, may have systemic effects. Properties of the corticosteroid and the patient, duration of treatment, size and location of the skin surface play a major role. These side effects can range from obvious Cushing's syndrome or a potentially life-threatening adrenal insufficiency, to more subtle effects such as weight gain and insulin resistance.

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Nederlands Tijdschrift voor Dermatologie en Venereologie
Erasmus MC: University Medical Center Rotterdam

van Rossum, L., Savas, M. (M.), & Wester, V. (2016). Lokale corticosteroïden en de relatie met obesitas. Nederlands Tijdschrift voor Dermatologie en Venereologie, 26(4), 206–210. Retrieved from