In this work, a novel magnetic resonance (MR)-compatible microwave antenna was designed and validated in a small animal superficial hyperthermia applicator. The antenna operates at 2.45 GHz and matching is made robust against production and setup inaccuracies. To validate our theoretical concept, a prototype of the applicator was manufactured and tested for its properties concerning input reflection, sensitivity for setup inaccuracies, environment temperature stability and MR-compatibility. The experiments show that the applicator indeed fulfils the requirements for MR-guided hyperthermia investigation in small animals: it creates a small heating focus (<1 cm3), has a stable and reliable performance (S11< −15 dB) for all working conditions and is MR-compatible.

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Keywords Hyperthermia antenna, microwave applicator, MR-compatibility, small animal heating systems
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Journal International Journal of Hyperthermia
Raaijmakers, E.A.L. (Elles A. L.), Mestrom, R.M.C, Sumser, K. (K.), Salim, G. (Ghassan), van Rhoon, G.C, Essers, J. (Jeroen), & Paulides, M.M. (2017). An MR-compatible antenna and application in a murine superficial hyperthermia applicator. International Journal of Hyperthermia, 1–7. doi:10.1080/02656736.2017.1369172