In the last two decades specific point mutations in oncogenes have been identified in urinary bladder cancers. Identification of these mutations in clinical samples (e.g., urine or tumor tissue) can be of use for diagnostic or prognostic purposes. In this chapter we describe how mutations in multiple oncogenes can be identified with a simple assay.

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Keywords DNA isolation, FGFR3, Mutation analysis, Oncogenic mutations, PIK3CA, RAS, TERT
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Series Methods in Molecular Biology
Note e-book; not purchased
Alamyar, M, & Zwarthoff, E.C. (2018). Analysis of point mutations in clinical samples of urothelial carcinoma. In Methods in Molecular Biology. doi:10.1007/978-1-4939-7234-0_2