The premature fusion of skull sutures, craniosynostosis, occurs in approximately 1 in 1500 births and results in a altered skull shape and increased risk of intracranial hypertension. This thesis focused on several aspects of unisutural craniosynostosis, in which only 1 suture is affected and closed prematurely.
In conclusion, this thesis has travelled from prenatal detection to long term postoperative follow-up. Considering the above, the answer to the question posed on the cover of this thesis ‘Unisutural Craniosynostosis: Simple or Complex’ really is simple: complex. The full range of clinical care that is warranted in the care for patients with unisutural craniosynostosis demands a highly specialized center, with high standards of patient care, research and education.

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I.M.J. Mathijssen (Irene) , T.E. Cohen-Overbeek (Titia)
Erasmus University Rotterdam
Over the course of this thesis (financial) support was provided by: Fonds NutsOhra, Stichting Hoofdzaak, Stichting Het Scholten-Cordes Fonds NVPC, JVPC, Maatschap Plastische Chirurgie EMC, BlooMEDical, van Wijngaarden Medical, Quamedical, Livit Orthopedie, Chipsoft, Kortjakje
Department of Plastic and Reconstructive Surgery

Cornelissen, M. (2017, October 13). Unisutural craniosynostosis: simple or complex?. Retrieved from