In neonatal intensive care units performing continuous EEG monitoring, there is an unmet need for around-the-clock interpretation of EEG, especially for recognizing seizures. In recent years, a few automated seizure detection algorithms have been proposed. However, these are suboptimal in detecting brief-duration seizures (< 30s), which frequently occur in neonates with severe neurological problems. Recently, a multi-stage neonatal seizure detector, composed of a heuristic and a data-driven classifier was proposed by our group and showed improved detection of brief seizures. In the present work, we propose to add a third stage to the detector in order to use feedback of the Clinical Neurophysiologist and adaptively retune a threshold of the second stage to improve the performance of detection of brief seizures. As a result, the false alarm rate (FAR) of the brief seizure detections decreased by 50% and the positive predictive value (PPV) increased by 18%. At the same time, for all detections, the FAR decreased by 35% and PPV increased by 5% while the good detection rate remained unchanged.

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Persistent URL dx.doi.org/10.1109/EMBC.2017.8037441, hdl.handle.net/1765/102614
Conference 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
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Citation
Ansari, A.H, Cherian, P.J, Caicedo, A. (A.), de Vos, M, Naulaers, G, & van Huffel, S. (2017). Improved neonatal seizure detection using adaptive learning. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 2810–2813). doi:10.1109/EMBC.2017.8037441