Variable sensitivity in molecular detection of zika virus in european expert laboratories: External quality assessment, November 2016

Charrel, Remi; Mögling, Ramona; Pas, Suzan; Papa, Anna; Baronti, Cecile; Koopmans D.V.M., Marion; Zeller, Hervé; Leparc-Goffart, Isabelle; Reusken, Chantal

doi:10.1128/JCM.00987-17

R. Charrel (Remi), R. Mögling (Ramona), S.D. Pas (Suzan), A. Papa (Anna), Baronti, C. (Cecile), M.P.G. Koopmans D.V.M. (Marion), H. Zeller (Hervé), I. Leparc-Goffart (Isabelle) and C.B.E.M. Reusken (Chantal)

2017-11-01

Variable sensitivity in molecular detection of zika virus in european expert laboratories: External quality assessment, November 2016

Journal of Clinical Microbiology , Volume 55 - Issue 11 p. 3219- 3226

Zika virus (ZIKV) infections are a significant public health concern. A strong capability for ZIKV detection is an absolute requirement for adequate preparedness and response strategies and individual patient care. The objective of this study was to assess and improve the capability of European expert laboratories for molecular testing for ZIKV through an external quality assessment (EQA) scheme. Laboratories were provided a panel of 12 samples which included negative samples, samples containing African- or Asian-lineage ZIKV at various concentrations (103 to 109 copies/ml), and samples containing dengue virus, yellow fever virus, or chikungunya virus. The results were analyzed on the basis of the outcomes of testing for the samples and the extraction and detection method used. Samples with a ZIKV RNA status scored correctly by.

Additional Metadata
Keywords	EQA, EVD-LabNet, External quality assessment, Laboratory preparedness, Laboratory response, Zika virus
Persistent URL	doi.org/10.1128/JCM.00987-17, hdl.handle.net/1765/102622
Journal	Journal of Clinical Microbiology
Organisation	Department of Virology
Citation APA Style AAA Style APA Style Cell Style Chicago Style Harvard Style IEEE Style MLA Style Nature Style Vancouver Style American-Institute-of-Physics Style Council-of-Science-Editors Style BibTex Format Endnote Format RIS Format CSL Format DOIs only Format	Charrel, R., Mögling, R., Pas, S., Papa, A., Baronti, C. (Cecile), Koopmans, M., D.V.M., … Reusken, C. (2017). Variable sensitivity in molecular detection of zika virus in european expert laboratories: External quality assessment, November 2016. Journal of Clinical Microbiology, 55(11), 3219–3226. doi:10.1128/JCM.00987-17

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note Reply to Baylis et al., “External Quality Assessment (EQA) of molecular detection of Zika Virus: Value of the 1st world health organization international standard” C.B.E.M. Reusken (Chantal) and Charrel, R. (Remi)

Variable sensitivity in molecular detection of zika virus in european expert laboratories: External quality assessment, November 2016

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Variable sensitivity in molecular detection of zika virus in european expert laboratories: External quality assessment, November 2016

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note Reply to Baylis et al., “External Quality Assessment (EQA) of molecular detection of Zika Virus: Value of the 1st world health organization international standard”

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Reply to Baylis et al., “External Quality Assessment (EQA) of molecular detection of Zika Virus: Value of the 1st world health organization international standard”