It is estimated that each year, 30,000 people in the Netherlands suffer from myocardial infarction, and is in fact a major public health care burden. Next to ischaemic heart disease (IHD), thanks to modern medicine, more and more patients with congenital heart disease (CHD) reach adulthood, but nonetheless require lifelong professional care. Imaging techniques are essential in these two groups of patients for establishing diagnosis, guiding therapy and predicting outcomes. This thesis investigated the application of cardiac MRI in patients with IHD and CHD and evaluated novel non-invasive MRI techniques in both humans and in a porcine model. In this thesis we showed that cardiac MRI is an excellent tool for the evaluation of atherosclerotic and congenital cardiovascular disease. It is an excellent tool in predicting outcome after STEM! in patients undergoing primary percutaneous coronary intervention. Furthermore, studied in this thesis, the incidence of per procedural complications in patients with CHD seems higher than in the general population suggesting that placement of a pacemaker device might be challenging in this group of patients.

Additional Metadata
Keywords MRI, Ischemic Heart Disease, Congenital Heart Disease, STEMI
Promotor R.J.M. van Geuns (Robert Jan) , G.P. Krestin (Gabriel) , O.C. Manintveld (Olivier)
Publisher Erasmus University Rotterdam
Sponsor Stichting Dira, Nieuwerkerk aan den IJssel
ISBN 978-94-92683-63-2
Persistent URL
Grant This work was funded by the European Commission 7th Framework Programme; grant id fp7/261409 - The MEtabolic Road to DIAstolic Heart Failure (MEDIA)
van Kranenburg, M. (2017, November 10). Application of Quantitative MRI Techniques in Ischemic and Congenital Heart Disease image-guided therapy. Erasmus University Rotterdam. Retrieved from