2017-11-21
TGF-β Gives an Air of Exclusivity to Alveolar Macrophages
Publication
Publication
Immunity , Volume 47 - Issue 5 p. 807- 809
Tissue-resident macrophages shape the development and homeostasis of the organs that they colonize. Yu et al. (2017) demonstrate that, unique to the lung, the instructive cytokine TGF-β collaborates with GM-CSF to induce the master transcription factor PPARγ to drive alveolar macrophage differentiation and maintenance early in life. Tissue-resident macrophages shape the development and homeostasis of the organs that they colonize. Yu et al. (2017) demonstrate that, unique to the lung, the instructive cytokine TGF-β collaborates with GM-CSF to induce the master transcription factor PPARγ to drive alveolar macrophage differentiation and maintenance early in life.
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| doi.org/10.1016/j.immuni.2017.11.005, hdl.handle.net/1765/103043 | |
| Immunity | |
| Organisation | Department of Pulmonology |
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Lambrecht, B. (2017). TGF-β Gives an Air of Exclusivity to Alveolar Macrophages. Immunity, 47(5), 807–809. doi:10.1016/j.immuni.2017.11.005 |
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