Postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and pituitary enlargement in primary hypothyroidism
We report a 36-year-old woman with primary hypothyroidism revealed by postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and suprasellar pituitary enlargement on magnetic resonance imaging (MRI). On thyroid hormone replacement therapy all clinical, biochemical, radiological and endocrine abnormalities disappeared. Hyperplasia of pituitary thyrotrophs and/or lactotrophs seems to be responsible for the pituitary enlargement seen on MRI.
|*Postpartum Period, Adult, Amenorrhea/*etiology, Female, Galactorrhea/*etiology, Humans, Hyperprolactinemia/*complications, Hypothyroidism/complications, Magnetic Resonance Imaging, Pituitary Gland/*pathology, Pregnancy, Thyroxine/therapeutic use|
|The Netherlands Journal of Medicine|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Kroese, J.M, Grootendorst, A.F, & Schelfhout, L.J. (2004). Postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and pituitary enlargement in primary hypothyroidism. The Netherlands Journal of Medicine. Retrieved from http://hdl.handle.net/1765/10329