Although perioperative outcome in transplant and surgical oncology patients has greatly improved during the last decades, preoperative risk assessment remains of utmost importance to further improve outcomes and adapt patient-tailored treatment strategies. Low skeletal muscle mass is associated with increased age and disease, such as cancer and liver disease. Considering the increasing age of the population, the increasing incidence of cancer, the remaining shortage of donor livers, and the increased surgical and medical treatment options, skeletal muscle mass could be an important addition used for risk assessment. Moreover, it may be a therapeutic target to improve treatment outcomes. Therefore, the aim of this thesis was to investigate the applicability of skeletal muscle mass measurements and to define the relevance of decreased skeletal muscle mass in surgical oncology and liver transplant patients.

Additional Metadata
Keywords Muscle mass, muscle density, computed tomography, sarcopenia, surgery, cancer, colorectal cancer, perihilar cholangiocarcinoma, cirrhosis, liver transplantation
Promotor J.N.M. IJzermans (Jan) , R.W.F. de Bruin (Ron) , B. Groot Koerkamp (Bas)
Publisher Erasmus University Rotterdam
ISBN 978-94-6295-771-8
Persistent URL hdl.handle.net/1765/103489
Citation
van Vugt, J.L.A. (2017, December 20). The impact of low skeletal muscle mass in abdominal surgery. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/103489