Aims To describe the safety and performance of STENTYS self-expandable bare metal stents (BMS) versus paclitaxel-eluting stents (PES) in saphenous vein grafts (SVGs). Methods and Results A randomised controlled trial was performed in four hospitals in three European countries between December 2011 and December 2013. Patients with de novo lesions (>50% stenosis) in an SVG with a diameter between 2.5–6 mm were included. Primary endpoint was late lumen loss at 6 months. Secondary endpoints included procedural success and the occurrence of major adverse cardiac events (MACE) at 12 months. A total of 57 patients were randomised to STENTYS self-apposing BMS (n = 27) or PES (n = 30). Procedural success was obtained in 89.5%. No significant differences in late lumen loss were found between BMS and PES at 6 months (0.53 mm vs 0.47; p = 0.86). MACE rates at 12 months were comparable in both groups (BMS 22.2% vs. PES 26.7%; p = 0.70). Conclusions Treatment of SVGs with STENTYS self-expandable stents is safe and effective. No significant differences were found in late lumen loss and MACE between BMS and PES.

Additional Metadata
Keywords Bare metal stent, Drug-eluting stent, Percutaneous coronary intervention, Saphenous vein grafts, Self-apposing stent
Persistent URL dx.doi.org/10.1007/s12471-017-1066-0, hdl.handle.net/1765/104581
Journal Netherlands Heart Journal
Citation
IJsselmuiden, A.J.J, Simsek, C, Van Driel, A.G. (A. G.), Bouchez, D. (D.), Amoroso, G, Vermeersch, P, & Karjalainen, P.P. (P. P.). (2018). Comparison between the STENTYS self-apposing bare metal and paclitaxel-eluting coronary stents for the treatment of saphenous vein grafts (ADEPT trial). Netherlands Heart Journal, 26(2), 94–101. doi:10.1007/s12471-017-1066-0