Aim: To examine the association between a healthy diet, assessed by the Healthy Diet Indicator (HDI), and cognitive decline in older adults.
Methods: Data from 21,837 participants aged ≥ 55 years from 3 cohorts (Survey in Europe on Nutrition and the Elderly, a Concerted Action[SENECA], Rotterdam Study [RS], Nurses’ Health Study [NHS]) were analyzed. HDI scores were based on intakes of saturated fatty acids, polyunsaturated fatty acids, mono- and disaccharides, protein, cholesterol, fruits and vegetables, and fiber. The Telephone Interview for Cognitive Status in NHS and Mini-Mental State Examination in RS and SENECA were used to assess cognitive function from multiple repeated measures. Using multivariable-adjusted, mixed linear regression, mean differences in annual rates of cognitive decline by HDI quintiles were estimated.
Results: Multivariable-adjusted differences in rates in the highest versus the lowest HDI quintile were 0.01 (95% CI –0.01, 0.02) in NHS, 0.00 (95% CI –0.02, 0.01) in RS, and 0.00 (95% CI –0.05, 0.05) in SENECA with a pooled estimate of 0.00 (95% CI –0.01, 0.01), I 2 = 0%.
Conclusions: A higher HDI score was not related to reduced rates of cognitive decline in European and American older adults.

Ageing · Diet · Nutrition · CHANCES · Cognition · Cohort · Epidemiology · Healthy Diet Indicator,
Dementia and Geriatric Cognitive Disorders
This work was funded by the European Commission 7th Framework Programme; grant id fp7/242244 - Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES)
Department of Epidemiology

Berendsen, A.A.M, Kang, J.H, van de Rest, O, Jankovic, N, Kampman, E, Kiefte-de Jong, J.C, … de Groot, L.C.P.G.M. (2017). Association of Adherence to a Healthy Diet with Cognitive Decline in European and American Older Adults. Dementia and Geriatric Cognitive Disorders, 43(3-4), 215–227. doi:10.1159/000464269