Invasive aspergillosis is the most common invasive fungal disease in patients with acute myeloid leukemia and recipients of allogeneic hematopoietic stem cell transplantation. Not only does it lead to a considerable morbidity and mortality, but also to an increase in medical costs. Triazole resistance in A. fumigatus has emerged over the past decade and is posing a worrisome challenge for diagnostics and treatment. Given these facts, it is essential to optimize the management of invasive aspergillosis in this patient group. This thesis focusses on invasive aspergillosis in high-risk patients with an underlying hematological disease and in particular on its epidemiology, prevention and diagnostics.

Additional Metadata
Keywords Invasive aspergillosis, hematology, triazole resistance, diagnostics.
Promotor A. Verbon (Annelies) , J.J. Cornelissen (Jan) , B.J.A. Rijnders (Bart)
Publisher Erasmus University Rotterdam
ISBN 978-94-6361-102-2
Persistent URL hdl.handle.net/1765/105957
Note For copyright reasons there is an embargo for chapter two of this dissertation.
Citation
Chong, G.-L.M. (2018, June 5). Invasive Aspergillosis in Clinical Hematology : diagnosis and impact on triazole resistance. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/105957


Additional Files
Cover-image.PNG Cover Image , 228kb
GLM-Chong-Stellingen.pdf , 14kb
Chapter-01.pdf Final Version , 957kb
Chapter-03.pdf Final Version , 979kb
Chapter-04.pdf Final Version , 1mb
Chapter-05.1.pdf Final Version , 3mb
Chapter-05.2.pdf Final Version , 1mb
Chapter-06.pdf Final Version , 1mb
Chapter-07.pdf Final Version , 1mb
Chapter-08.pdf Final Version , 966kb
Chapter-09.pdf Final Version , 974kb