2018
Catheter design optimization for practical intravascular photoacoustic imaging (IVPA) of vulnerable plaques
Publication
Publication
Presented at the
Diagnostic and Therapeutic Applications of Light in Cardiology 2018 (January 2018), San Francisco
Intravascular photoacoustic/ultrasound imaging (IVPA/US) can image the structure and composition of atherosclerotic lesions identifying lipid-rich plaques ex vivo and in vivo. In the literature, multiple IVPA/US catheter designs were presented and validated both in ex-vivo models and preclinical in-vivo situations. Since the catheter is a critical component of the imaging system, we discuss here a catheter design oriented to imaging plaque in a realistic and translatable setting. We present a catheter optimized for light delivery, manageable flush parameters and robustness with reduced mechanical damage risks at the laser/catheter joint interface. We also show capability of imaging within sheath and in water medium.
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doi.org/10.1117/12.2287364, hdl.handle.net/1765/106474 | |
Diagnostic and Therapeutic Applications of Light in Cardiology 2018 | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Iskander-Rizk, S., Wu, M., Springeling, T., Mastik, F., Beurskens, R., van der Steen, T., & van Soest, G. (2018). Catheter design optimization for practical intravascular photoacoustic imaging (IVPA) of vulnerable plaques. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. doi:10.1117/12.2287364 |