Clinical features and treatment of keratoderma hereditaria mutilans (Vohwinkel's syndrome) are described in an 11-year-boy. The disease, in particular the mutilating complications (pseudo-ainhum), responded satisfactorily to the oral administration of etretinate, an aromatic retinoid.

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Journal Archives of Dermatology
Chang Sing Pang, A.F.I. (Albert F. I.), Oranje, A.P, Vuzevki, V.D. (Vojislav D.), & Stolz, E. (1981). Successful Treatment of Keratoderma Hereditaria Mutilans With an Aromatic Retinoid. Archives of Dermatology, 117(4), 225–228. doi:10.1001/archderm.117.4.225