An uncommon presentation of molar pregnancy is a twin gestation with a normally developed fetus alongside a complete hydatidiform mole. Since the pregnancy of the normally developed fetus can progress to a viable term, continuation of a complete hydatidiform mole (CHM) can be allowed, whereby severe maternal molar-associated complications could develop. In this article we describe the pathophysiology and potential severe maternal mole-related morbidity associated with an ongoing molar pregnancy. Understanding the possibility of reaching a viable term of the healthy co-twin, and being aware of the risks of continuing a CHM pregnancy, is an essential part of informed and shared decision-making.

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Journal of Reproductive Medicine
Erasmus MC: University Medical Center Rotterdam

Erkamp, J., ten Kate-Booij, M., Ewing, P., & Schoenmakers, S. (2018). Classical symptoms and risks associated with an ongoing molar pregnancy in case of a coexisting twin. Journal of Reproductive Medicine, 63(3), 249–253. Retrieved from